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Preventing ACEs would have a profound effect on both individual and population health
For instance, individuals with a genetic predisposition to poor toxin clearance are more vulnerable to its effects
doi: 10.1016/j.jprot.2011.05.013

The dysregulation of zinc-dependent zinc finger proteins and hormone receptors has been associated with various human diseases, including neurodevelopmental disorders and cancer progression 106,107,108,109,110,111,112
The two major transcription factors: i) the NFB upregulates the pro-oxidant mediators, and ii) the Nrf2 activates the antioxidant responses 622