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121 introduced microneedles loaded with temozolomide (TMZ) and MnCl 2 (TMZ/MnCl 2 @HMN) for local transdermal drug release in melanoma chemoimmunotherapy

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Finally, the bifunctional flavokinaze/FAD-synthase encoded by the Bacillus gene, ribFC , catalyzes the conversion of riboflavin to FMN and FAD involved in oxidation-reduction reactions at all cellular levels (Revuelta et al., 2016

Although BHB had no direct effect on NMDA-evoked neurotransmitters, BHB was found to increase neurotransmitter release upon stimulation with the KATP channel blocker, glibenclamide, indicating the involvement of K ATP channels in the effects exhibited by BHB [198]

also, the activities of antioxidant enzymes were elevated [37]

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