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Handy DE, Loscalzo J

Similarly, several soybean glyoxalase members such as GmGLYI 6, GmGLYI 9, GmGLYI 20, GmGLYII 5, and GmGLYII 10 were reported for their highly abiotic stress responsive expression ( GmGLYI -6/9, GmGLYI -20, GmGLYII -6, and GmGLYII -10 showed biotic stress specific modulation in response to various pathogenic infection ( Medicago glyoxalase genes was further analyzed in response to two devastating abiotic stresses-salinity and drought ( Figure 10 )

Furthermore, this process works in concert with System Xc inhibition and GPX4 inactivation to exacerbate lipid peroxidation, ultimately triggering ferroptosis (Hou et al

10.3892/mmr.2015.3500 134 WangY.HuangG.MoB.WangC

The liver is a key target organ for methylation reactions where SAM is the methyl donor (Figure 1(a)) and participates in posttranslational protein modifications, DNA and histone tail methylation, as well as many metabolic pathways such as creatine synthesis [1315], carnitine synthesis [16, 17], and endogenous phosphocholine synthesis [18]