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Melatonin can increase the expression of antioxidant enzymes (such as SOD and CAT) and inhibit the excessive production of ROS 264

To protect the cell from a shift in the redox equilibrium, GSSG can be actively exported out of the cell or react with a protein sulfhydryl group leading to the formation of a mixed disulfide

He found that this timing helped him feel more refreshed upon waking

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this was found to have a significant effect on progression to requiring treatment in early PD

Calkins MJ, Vargas MR, Johnson DA, Johnson JA (2010) Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition