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And that's how they do all of them

The development of biodegradable and biocompatible bone cements may further improve therapeutic outcomes, promote natural bone healing, and reduce the risks associated with long-term use of permanent bone cement

They do not fade on their own: Unlike post-inflammatory hyperpigmentation, icepick scars are structural tissue deficits that require clinical intervention for meaningful improvement

Cellular and Molecular Mechanism Underlying the Pathogenesis of Neurodegeneration in PD 3.1

This is a normal and expected response, not a side effect to be concerned about

Bull Exp Biol Med 135(6):590592