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Nadph oxidases: from molecular mechanisms to current inhibitors

TRIF/TRAM, TRIF (TLR4 signaling)-related adapter molecule (TRAM)

Copp J P, Desprez P Y, Krtolica A, et al

This mechanism involves promoting E3 ubiquitin-protein ligase (SMURF1) gene expression following miR-153-3p adsorption, facilitating protein-protein interactions and the ubiquitination-mediated destruction of 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 (PFKFB3)

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