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PMID: 41896977

Notable variants utilized for catalyzing aromatic hydroxylation reactions are RT2, KT2, and R19, all of which harbor 5 to 7 mutations

In contrast, research and publications on CUP in veterinary medicine are exceedingly rare, with only a handful of studies available

Side effects appear to be infrequent and mild in most reported cases, and may include: Temporary injection site reactions (with subcutaneous administration) Mild headache in some individuals Vivid dreams often considered a sign of enhanced REM sleep activity Occasional mild gastrointestinal discomfort DSIP does not appear to suppress respiratory function or cause the cognitive impairment sometimes associated with sedative-hypnotic drugs

Finally, the authors would like to thank their families for their unwavering support and understanding during the research and writing process

Table 1 presents the mechanisms of antioxidant action of NAC