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doi: 10.1039/D2RA08284E

Introduction The gastrointestinal (GI) system plays a central role in human health as the primary site for digestion and nutrient absorption, while also influencing immunity, endocrine signaling, and mental well-being through the gutbrain axis

10.1186/s12918-016-0281-4 22 BarbosaJ

The release of pro-inflammatory cytokines such as IL-1, IL-6, TNF-, and IL-17 leads to increased immune-cell activation and recruitment, creating an environment conducive to viral replication [2]

Zhang Y, Nguyen TTT, Shang E, Mela A, Humala N, Mahajan A, et al

Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting