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237 Creatine, an amino acid derivative synthesized from L-arginine, glycine, and L-methionine, has been extensively investigated in the context of tumor progression

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Nitrosamines such as NNK and NNN are activated independently of AHR via CYP2A6 and CYP2A13, and also contribute to DNA adduct formation and carcinogenic processes (3, 67, 68)
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