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20,21 A lack of GCase and the resultant glucosylceramide build-up promotes increased formation of abnormal oligomers of S

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To date, three isoforms of Trx have been identified in mammalian cells: Trx1 (cytosolic), Trx2 (mitochondrial), and SpTrx (spermatozoa cells) ( 2 O 2 and lipid hydroperoxide, in addition to TrxS 2

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doi: 10.1016/bs.irn.2020.01.005 93