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Vitamin Supplementation Initiate folic acid 400 mcg to 1,000 mcg orally once daily, beginning 7 days before the first dose of pemetrexed for injection and continuing until 21 days after the last dose of pemetrexed for injection [see Warnings and Precautions (5.1)]

However, Vitamin B12 has many more functions than red blood cell production

Most peptides have minimal drug interactions

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Ethics declarations Ethics approval and consent to participate This study received approval from the Institutional Review Board (IRB) of the Federal University of Minas Gerais (UFMG) (CAAE3768820.1.0000.5149)

Inject slowly intravenously