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It is possible that oxidation of the GSH pool also results in 2Fe-2S cluster disassembly and activation of Grx2 via an initial liberation of GSH from the complex

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Alzheimers disease (AD), the most common type of dementia in the elderly, is a serious neurodegenerative disease which is associated with progressive cognitive deterioration, such as memory loss and logical reasoning ability decline [8]

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Next, to understand the Cu uptake properties of Cu 3 -TC-Py, we conducted ICP-MS experiments to measure the total Cu content in A549, MDA-MB-231, and PC3 cell lines post-treatment with Cu 3 -TC-Py at 48 and 72 h (Fig