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Platelet-derived MHC class I confers a pseudonormal phenotype to cancer cells that subverts the antitumor reactivity of natural killer immune cells

E.ChenL.NaR.LiuY.RiosC.Van RemmenH.et al (2012)

A novel GSK-3 inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway

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Zinc signaling is essential for NETosis, as zinc chelation by TPEN inhibits this process without affecting PKC activity or ROS production, suggesting zinc acts downstream of ROS [161]

For this reason intracellular copper homeostasis is critical and is carried out by a number of copper binding proteins and copper chaperones