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In fact, lysosomal damage not only disrupts intracellular clearance but also results in the leakage of multiple contents, which pose great threats to the cell by triggering cell death pathways, including apoptosis, necroptosis, pyroptosis, and ferroptosis

Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability
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Targeting the antioxidant defense mechanisms of cancer cells has emerged as a promising therapeutic strategy
