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However, in the mouse brain, L-carnitine supplementation has been shown to increase brain 5-HT concentration ( 10 , increased low peripheral serotonin values ( Limitations of the study include a relatively small non-randomized retrospective clinical sample

doi: 10.3390/ijms21031047

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A Bianchetti, R Rozzini, M Trabucchi, 2003 - The effects of L-carnitine supplementation on glycemic markers in adults: A systematic review and dose-response meta-analysis

Ji Q, Zhang L, Jia H, Xu J

Lastly, despite PDE5i treatment has been proven a cost-effective therapeutic strategy, compared to no treatment [62], the relatively high cost of a chronic treatment with some reference/equivalent pharmaceutical formulations belonging to this category of drugs might still represent a limitation for patients with economic constraints, by contributing to treatment discontinuation