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10.1016/j.jcf.2021.01.010 J Cyst Fibros
Quantification of 2HG enantiomers 2HG quantification in SCD erythroblasts was performed as we previously described 24 by liquid chromatographymass spectrometry (LC-MS/MS) after derivatization using N-(p-Toluenesulfonyl)-L-phenylalanyl Chloride (TSPC) on the LC-ESI-MS/MS system
Similar studies with starch and amylase were carried out in the 1920s through 1940s by other investigators
Myo-Ins amplifies ATP-mediated Ca responses in normal dermal fibroblasts Given that Myo-Ins is a precursor of inositol phosphates and PIP, which regulate Ca dynamics, we examined its effects on intracellular Ca signalling in normal fibroblasts
GM2-activator deficiency
Acetaminophen, in particular, is known to produce a toxic metabolite that is normally detoxified by glutathione
