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doi: 10.1016/j.bbagrm.2021.194734
Phyther Res [Internet]
However, in later stages, both NO- and EDHF-induced vasodilation may eventually be impaired, resulting in microvascular dysfunction (41)
In particular, the biochemical analysis revealed the accumulation of MMA and alteration of metabolites in vB12-related pathways in the brain of adult Tbx1 +/ mice, and in mice carrying a multigenic deletion ( Df1/ + ) of 22q11.2DS orthologs that includes Tbx1 (19)
Schedule: Daily subcutaneous administration for 812 weeks, with an optional extension up to 16 weeks
95% CI, 1.01-1.02
