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Since many of my patients have MTHFR mutations ( gene mutations that make it more difficult for the body to convert cyanocobalamin into an active form of B12 ), I prefer to avoid this type of B12 supplementation

Vitamins, including A and C, and minerals like zinc and magnesium are often marketed for helping immunity, and according to Hancock, "in most of those cases there is a very, very good body of evidence that suggests that they're beneficial." Hancock says he takes a multivitamin every day
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doi: 10.1016/j.ejpb.2018.06.011
Yes, B12 can interact with some medications

used an intravenously administered alcohol clamp and found that a high-carb meal, but not an equicaloric high-fat or high-protein meal, increased AER (190)
