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144 A more recent meta-analysis by Yang et al examined metformin use and neuropathy and found no association, highlighting similar issues in terms of the lack of randomised controlled trials, small sample size and varying study design as described above

Food and Drug Administration, and these products are not intended to diagnose, treat, cure, or prevent any disease.

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However, Wnt/-catenin signaling activation promotes the development of liver cancer and the resistance to immunotherapy (Zhou et al., 2022