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Ranjeva, S

10 Apparently, mutant or deficient ABCB7 plays an important role in the pathogenesis of mitochondrial iron accumulation

Small pieces of cell debris and a very limited number of dead cells observed on the dentin surface without biofilm structure may be related to physicochemical linkages between cells and dentin surface because cell viability has limited influence on attachment, as suggested by previous studies.27,32 It seems that NAC at the concentrations from 25 to 50mg/mL can remove the mature multispecies biofilm partially, but was still able to effectively kill the bacteria located in the remaining biofilm that was at most a few cell layers thick

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Clinically, Bushen Huoxue Granule was proved to be effective in treating PD for many years, a Chinese herbal compound granule (Li et al., 2012)