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observed that DKD patients exhibit significant downregulation of glycine metabolic pathways, reduced glutathione levels, a decreased glutathione to oxidized glutathione ratio, and elevated malondialdehyde, contributing to cellular oxidative stress

Table 3)

the conjugate of the invention is anti-EphA2-valine-citrulline-MMAE (anti-EphA2-val-citMMAE or anti-EphA2-vcMMAE), or anti-EphA2-valine-citrulline-MMAF, or anti-EphA2-malaeimidocaproyl-citrulline-MMAE, or anti-EphA2-malaeimidocaproyl-citrulline-MMAF, or anti-EphA2-valine-citrulline-AEFP (anti-EphA2-val-citAEFP or anti-EphA2-vcAEFP)
1 IVF has been reported to be associated with a pregnancy rate of 3.147.6%, depending on the age of the female partner

Chemistry, Ninth Edition
