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small-molecule inhibitors Current therapeutic approaches comprise small-molecule inhibitors such as Fer-1, iron chelators, and genetic modifications [225, 226]

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*Indicates that the p -value was calculated based on the final and baseline values of participants in the TRF group because no comparison was made between changes in values in a TRF group and a normal diet control group in the original manuscript

ALA is widely distributed in various tissues, with significant concentrations found in the liver, heart, and skeletal muscle