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Modifier 59 and CPT 96372: When and How to Use It Modifier 59 signals a "Distinct Procedural Service." Use it with 96372 when a second or subsequent injection is given at the same visit, involving a different drug administered at a different anatomical site

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NHS Guidelines on Self-Administering B12 Injections The NHS supports patient self-administration of B12 injections where clinically appropriate and following adequate training

Use under medical supervision: Only take this injection if prescribed by your doctor

Multiple injections at the same visit require Modifier 59 on each additional line and separate documentation for each injection site and drug