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Treatment of the BV2 cell line with -synuclein increases the secretion of exovesicles expressing the MHC Class II and TNF- molecules on the surface as well as inducing neuronal apoptosis (Chang et al., 2013)

Specifically, CBD significantly reduces cell viability, likely through antagonizing the transient receptor potential melastatin type-8 (TRPM8)

Anti-CD3 scFvs isolated from additional selection and screening can be benchmarked against this current standard

Cynader, Pyruvate Released by Astrocytes Protects Neurons from Copper-Catalyzed Cysteine Neurotoxicity

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