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The results of these trials will be pivotal in defining the precise role of MOTS-c in the clinical toolkit and moving it from the realm of experimental biology to evidence-based medicine

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Together, the two peptides have been studied for possible synergistic interactions when administered in combination

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Individuals with R116Q mutations in the PNPO gene have a milder phenotype, with some experiencing no seizures or late-onset symptoms and only mild to moderate mental retardation [36]

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