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doi: 10.1186/cc2337

2.4 Gene UL39 The UL39 gene is situated within the Unique Long Region of the HSV-1 genome and plays a critical role in viral replication and in modulating physiological processes within host cells ( ICP6, which is encoded by the UL39 gene and serves as the large subunit of ribonucleotide reductase, is vital for converting ribonucleotides into deoxyribonucleotides necessary for DNA synthesis in viruses ( Another significant function attributed to ICP6 involves its modulation of programmed cell death (PCD) processes in infected cells through its receptor-interacting protein-homotypic interaction motif (RHIM) ( Inactivation of ICP6 through fusion with LacZ results in restricted virus propagation primarily among dividing cells, particularly tumor cells capable of supplying deoxyribonucleotides via endogenous pathways ( 3 Inserting exogenous genes 3.1 GM-CSF Induction of immune cells to kill tumor cells is one of the key mechanisms of oncolytic virus anticancer

Storage: Lyophilized: freeze at 20 C (4 F)

How to Use: Apply evenly to face and neck in the morning & evening after cleansing

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