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Recent observational studies and RCT evidence suggest high selenium exposure may negatively impact cardio metabolism, especially hypertension, dyslipidemia, and type 2 diabetes (Vinceti et al., 2018

[DOI] [PubMed] [Google Scholar] Azirak S, Bilgic S, Korkmaz DT, et al

Ogata, M., Fryling, C

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Chrysophanol alleviates myocardial injury in diabetic db/db mice by regulating the sirt1/hmgb1/nf-kappab signaling pathway

Cohort 1 During the 21-day follow-up period, there were only four cases of SARS-CoV-2 infection in Cohort 1, evenly distributed between the LCLT ( n = 2) and placebo ( n = 2) groups and, therefore, the majority of the participants remained free of COVID-19 during the follow-up period