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643 Lecanemab and donanemab are FDA-approved mAbs that target A in distinct ways, both showing moderate benefits in clinical trials in slowing the rate of cognitive decline versus placebo, as evaluated by CDR-SB and iADRS scores, respectively

Unlike an acute rotator cuff tear, tendinopathy typically develops over time due to repetitive use, poor posture, age-related changes, or shoulder impingement