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Experiments need to be designed where the inhibitors/activators of the identified genes are administered simultaneously with various ASMs to evaluate the effects of their co-treatment

Oncotarget 6 , 4065540666 (2015)

In addition, a new study found that HA can increase OS imbalance and low-level inflammation in the ovary and upregulate the expression of inflammatory factors by activating NLRP3 inflammatory bodies, thereby inducing pyroptosis of ovarian granulosa cells, damaging follicular function and leading to ovulation disorders (73)

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