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Furthermore, DFO protects photoreceptor cells from ferroptosis caused by atRAL by decreasing Fe 2+ levels, total iron levels, and lactate dehydrogenase (LDH) levels (Chen et al., 2021)
What differs is how long therapeutic concentrations persist: SubQ maintains elevated levels for 46 hours due to gradual absorption, while IM peaks higher but returns to baseline within 23 hours
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Bromberg A, Lerer E, Udawela M, Scarr E, Dean B, Belmaker RH, Ebstein R, Agam G (2012) Nicotinamide- N -methyltransferase (NNMT) in schizophrenia: genetic association and decreased frontal cortex mRNA levels

The molecule's size and stability issues mean that not all of it penetrates deeply enough to create significant changes in melanin production

Jr..,MacKenzie W
