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However, challenges exist in the clinical application of Rg1, such as low bioavailability as well as a lack of comprehensive long-term safety and efficacy data

They improve mitochondrial function, reduce reliance on glycolysis, and restore normal metabolic patterns in multiple tissue types

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doi: 10.7759/cureus.14686 192 PoffAMAriCSeyfriedTNDAgostinoDP

Protocols vary some clinicians dose once daily before bed

Adaptation to prolonged or repeated stress comparison between rat strains showing intrinsic differences in reactivity to acute stress