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The pathogenesis likely involves upregulated porphyrins, which increase inflammation
Findings from the discovery cohort also identified numerous proteins that are associated with acute inflammation, redox balance and immune responses such as ORM1, ORM2 and Afamin (AFM) that were elevated in konzo affected children, perhaps identify additional future targets of investigation 44,45,46
Targeting mitochondrial structure sensitizes acute myeloid leukemia to venetoclax treatment
MTHFR is a crucial gene in the methylation cycle, which is instrumental to good health
