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Description
Cystine uptake determined the sensitivity of acute myeloid leukemia cells to APR-246 Since cysteine is a biosynthetic precursor of GSH, we asked whether the ability of cells to provide cysteine for GSH synthesis underlies the sensitivity to APR-246
They are used to deliver essential vitamins and minerals directly into the bloodstream

Bottom HBSS from an empty insert (without cells) treated only with HBSS was used as blank control to subtract basal fluorescence

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A high-dose IV gets around that limit

These conversions reflect the dilutions documented in community reconstitution protocols
