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Symptoms like fatigue, brain fog, low mood, and slow metabolism are common signs of B12 depletion

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Additionally, it protects the energy producing enzymes from attack by nitric oxide, promoting and sustaining energy production

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However, it is worth keeping the solubility tag for some experiments such as GST-pulldowns which leverage the molecular interaction between GST and glutathione to investigate which proteins or other molecules that your protein of interest binds to (Figure 2)