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Engineering light-controllable CAR T cells for cancer immunotherapy

I., Satriyo, K

PON1 , an enzyme that circulates in the blood attached to HDL cholesterol, metabolizes homocysteine-thiolactone back to homocysteine in the bloodstream

Later, the cells were labeled with 1 mM of the fluorescent dye carboxyfluorescein diacetate succinimidyl ester (CFSE, Vazyme, Nanjing, China)

its been our focus from Day 1

Pyruvate/lactate and acetoacetate/beta-hydroxybutyrate are indicators of the cytoplasmic and mitochondrial [NAD + ]/[NADH], respectively, while the malate/pyruvate and isocitrate/alpha-ketoglutarate are indicators of the cytoplasmic [NADPH]/[NADP + ]
