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In the upper small intestine where the pH changes to less acidic conditions, haptocorrin is degraded by pancreatic proteases, releasing B12 which subsequently becomes bound to gastric intrinsic factor (IF) to form the IFB12 complex

A.SchirmacherP.CastrnE.et al (2000)

doi: 10.3389/fcell.2020.00801 Received 16 December 2019 Accepted 28 July 2020 Published 26 October 2020 Volume 8 - 2020 Edited by Zhigang Ren, First Affiliated Hospital of Zhengzhou University, China Reviewed by Vigna Elisa, University of Turin, Italy

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[7] Mechanisms of Action Liothyronine is an L-isomer that binds with high affinity to nuclear thyroid hormone receptors (TR1, TR1, TR2) distributed across nearly every tissue

Effect of sulfation and molecular weight on anticoagulant activity of dextran