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Bibcode:2004PNAS..101.8569W

The reversible nature of Grx2 is associated with its sensitivity to changes in GSH/GSSG

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Therefore, based on meta-analyses of clinical trials, at present, no drug can be proposed as a gold standard to either prevent CIPN or treat its symptoms, and chemotherapeutic drug dose modification remains the only preventative strategy [41]

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Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation
