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4 more prevalent for folate deficiency

According to older research published in Though the condition is most common in people with darker skin tones, anyone can develop darker skin around the knees

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Singh A, Venkannagari S, Oh KH, Zhang YQ, Rohde JM, Liu L, et al

J Neurochem 94:16761684

Mechanistically, EGCG scavenges ROS, attenuates lipid peroxidation, and upregulates endogenous antioxidant defenses such as superoxide dismutase and glutathione peroxidase, thereby reducing oxidative stress-induced neuronal damage (145)