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[2] For most individuals taking standard B12 supplements as recommended by healthcare professionals, the risk of harmful effects remains extremely low

Fortunately, these side effects typically fade within a few weeks as the body adjusts to the medication

doi: 10.3390/nu15112525 Pubmed Abstract CrossRef Google Scholar View reference in article 70 GreenRAllenLHBjrke-MonsenA-LBritoAGuantJ-LMillerJWet al

Shiitake mushrooms that were sun-dried indoors at 26C for 36 h exhibited reduced levels of total phenolic content (93.4 to 3.9 mg/100 g in fresh shiitake), total antioxidants (109.5 to 5.4 mg/100 g in fresh shiitake), and scavenging activity (43.2 to 6.6%) in comparison to microwave and freeze-drying techniques (98)

+ It varies with the type of B12 and your own levels

Figure 6b,c