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doi: 10.1146/annurev.immunol.25.022106.141557 63 IvanovIIFrutos RdeLManelNYoshinagaKRifkinDBSartorRBet al
It is noteworthy that human and rodent KOR differ substantially in the amino acid composition in the C-terminal region
Bax promotes death
It also may explain why KPV appears to have a favorable safety profile compared to more aggressive immunosuppressive approaches
Because the peptides used in therapy are naturally occurring or bioidentical, the risk of serious side effects is very low
Some of the peptide may be broken down before it can exert its full effect on systemic tissues outside the gut
