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Synergistic anti-leukemic activity with combination of FLT3 inhibitor quizartinib and MDM2 inhibitor milademetan in FLT3-ITD mutant/p53 wild-type acute myeloid leukemia models

All studies were performed in accordance with the institutional guidelines

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Metabolism was halted at specific time intervals by precipitating proteins with acetonitrile and acetic acid

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