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Therapeutic Delivery, 4 (11), 1443

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Adrenergic signaling is a significant component of homeostasis regulation, and its dysfunction is associated with metabolic, mental, or neurodegenerative disorders (245)

This 'first-pass effect' exposes the compound to hepatic enzymes

doi: 10.1152/ajpregu.1994.267.6.R1431

While glutathione is generally well-tolerated, any supplement can cause side effects in some individuals