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Description
In an experimental model of ischemic optic neuropathy, treatment with bardoxolone methyl exerts a myelin-preserving impact on RGC survival, achieved by enhancing the transcription of ferroptosis-associated protective factors, namely HO-1 and NQO1 (141)
O., Ezim, O
doi: 10.3390/antiox9090878
[DOI] [PubMed] [Google Scholar] [27].Calabrese V, Sultana R, Scapagnini G, Guagliano E, Sapienza M, Bella R, Kanski J, Pennisi G, Mancuso C, Stella AM, Butterfield DA
Maintain a healthy lifestyle and follow your specialists recommendations
The role of Nrf2 in liver fibrosis has been clarified by Lu, who showed that GCL subunits and GS are regulated byNrf2, which binds AREs present in their promoters [2] (Figure 6)
