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CBS and CSE are located in the cytosol of cells, whereas 3MST primarily resides in and generates H 2 S in mitochondria

A fishy body odor may also develop in some users due to the supplement's metabolic breakdown

doi: 10.1074/jbc.M114.614578 34

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Pain 137(3):473477 Hunyady , Hajna Z, Gubnyi T, Scheich B, Kemny , Gaszner B, Borbly , Helyes Z (2019) Hemokinin-1 is an important mediator of pain in mouse models of neuropathic and inflammatory mechanisms