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These hybrid systems effectively merge material intelligence with digital wound management, paving the way for personalized, data-driven regenerative therapies

1 Introduction Gentiopicroside (GPS), a secoiridoid glycoside, is extensively found in numerous traditional medicinal plants, including Gentiana scabra Bunge, Swertia chirayita, and Picrorhiza kurroa (Patel et al., 2019

In addition, breast CSCs defined either as CD24 /Low CD44 + Lin or ALDH + showed elevated GSH concentration and glutathione synthesis enzymes[13,34], which, in the case of ALDH + cells, was further enhanced with upregulation of GPXs and GSTs[34,35]

Through multiple mechanisms including antioxidant activity, immune modulation, and gene expression regulation, GHK-Cu offers comprehensive support for skin health, tissue repair, and anti-aging applications

Conclusions and perspectives Since its discovery in 2012, the role of ferroptosis in regulating a variety of cellular processes and different diseases, especially cancer, has been extensively studied [179, 180]