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Most patients tolerate gastric slowing very well, especially when semaglutide doses are increased gradually over 46 weeks

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DeYoung MB, MacConell L, Sarin V et al (2011) Encapsulation of exenatide in poly-(D, L-lactide-co-glycolide) microspheres produced an investigational long-acting once-weekly formulation for type 2 diabetes

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