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The coactivator PGC-1 belongs to the family of PGC-1s coactivators, generally considered as master regulators of mitochondrial biogenesis and oxidative metabolism as well as of antioxidant response 22

The complex is stable, and under physiological conditions no release of ionic iron occurs
Insulin-Like Growth Factor-1 Inhibition of Apoptosis Is Associated With Increased Expression of the bcl-xL Gene Product

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