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Pharmacokinetic Analysis Pharmacokinetic analysis was performed using data from individual rats
Accordingly, decreased cAMP levels were observed in fly and mouse FXS models and a deregulation of cAMP and cGMP was also identified as a molecular hallmark in FXS patients (99, 100)
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[DOI] [PubMed] [Google Scholar] 208.Zambelli V.O., Fernandes A.C., Gutierrez V.P., Ferreira J.C., Parada C.A., Mochly-Rosen D., Cury Y
Given the high heterogeneity, further studies are needed to confirm the results
