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Premature capacitation and increased DNA fragmentation are linked to oxidative damage and mitochondrial dysfunction (128, 129)
108,109 The activity of the HCV core protein decreases the expression and activity of the nuclear PPAR-/, which, besides being strongly involved in lipid and lipoprotein metabolism, seem to have a protective effect against hepatic inflammation and fibrosis
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Journal of research in personality
Chronic use activates microglial cells in the cortical gray matter, thereby promoting inflammation and neurotoxicity
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