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The DCM model 5 included the oxidative stress biomarkers, GSH and MDA

Similarly, the IL-2-mediated expansion of peripheral Tregs in humans and mice has demonstrated efficacy in various neurological disorder models, including amyotrophic lateral sclerosis [254]

J Pharm Phytochemistry

Apigenin can also significantly relieve the intestinal pathological injury in these animal models, increasing goblet cell quantity and mucin secretion, promoting anti-inflammatory cytokines IL-10 expression, and inhibiting the expression of proinflammatory cytokines, TNF-, IL-1, IL-6, and MPO activity of colon tissue [64]